Mark Air Particulate Control Systems

Calibration of Bio Safety Cabinet || Calibration is the process of testing the accuracy of the readings of a measurement instrument and making any necessary adjustments if the instrument isn't working properly. 

The HEPA filter integrity test is typically performed on cleanroom supply air HEPA filters using a photometer to scan the filter surface for pinhole leaks that could allow the transmission of contaminant particles that would be unacceptable in a critical application.

The HEPA filter integrity test is typically performed on cleanroom supply air HEPA filters using a photometer to scan the filter surface for pinhole leaks that could allow the transmission of contaminant particles that would be unacceptable in a critical application.

PAO testing is a very quick process that tests the integrity of the HEPA (High Efficiency Particulate Air) filter using DOP or PAO solutions in their operational conditions. These solutions generate a gas type smoke and then generate gas particles that will be greater than . 03 microns.PAO testing is a very quick process that tests the integrity of the HEPA (High Efficiency Particulate Air) filter using DOP or PAO solutions in their operational conditions. These solutions generate a gas type smoke and then generate gas particles that will be greater than . 03 microns.

When we conduct the particle count test, air sample is taken from the room and passed though a chamber which scans the sample for particles of various sizes ranging from 10microns down to 0.3microns. Number of particles of each size is counted and displayed on the sceen and a print out is delivered at the end of each count. The particle counter is programmed to work as per ISO 14644 and calculates automatically based on the counts at various locations and delivers the result. The Particle Counter is Calibrated with traceability to NABL.  

Dispersed Oil Particulate (DOP) testing, also known as filter integrity testing, is the process in which the integrity of your HEPA (High Efficiency Particulate Air) or ULPA (Ultra Low Penetration Air) filter is challenged through introducing particulates and measuring the output.

PAO testing is a very quick process that tests the integrity of the HEPA (High Efficiency Particulate Air) filter using DOP or PAO solutions in their operational conditions. These solutions generate a gas type smoke and then generate gas particles that will be greater than . 03 microns.PAO testing is a very quick process that tests the integrity of the HEPA (High Efficiency Particulate Air) filter using DOP or PAO solutions in their operational conditions. These solutions generate a gas type smoke and then generate gas particles that will be greater than . 03 microns.

Professional Calibration Team with all Test Instuments.

Calibration of Clean Room HEPA filtration Systems particularly Laminar Flow Units, Biological Safety Cabinets, Clean Room HEPA filters is essential and has to be repeated atleast once a year.

The following Tests have to be carried out for Compliance to various Regulators / Standards:
(We undertake all of these and we own all these instruments. All instruments are Calibtrated with Traceability to NABL or National Standards)

All tests or selective tests can be carried out:

1. HEPA filter Integrity Test (PAO/DOP Test) as per IES-RP-CC
2. Room Particle Count Test with compliance to ISO or US Fed Standard
3. Air Velocity measurement
4. UV intensity
5. Pressure pressure Drop
6. Room Positive Pressure
7. Clean Room Air Changes and AHU capacity calculation/confirmation
8. Airflow Visualisation
9. Light intensity test using Lux meter
10. Noise level test

We do professional work and our charges are also economical.

NABL accredited Calibrators / Labs shall also contact us.

Scientific Instrument suppliers or agents shall also contact us.

We also undertake monthly / periodic testing service for Pharma mfrs, Hospitals, Labs and Institutions on Annual or per call basis.

Our credible services and validation has helped us in garnering multiple clients over the years. We stringently undertake HEPA tests for airflow velocity, uniformity, static pressure etc as per the standard norms. The HEPA filter integrity test is carried out as per IES recommendation, using an Imported Digital Photometer, which is, state-of-the-art and tamper proof. In fact, we offer our service for any make of Laminar Airflow/HEPA filtration equipment. The data gathered from these tests serve as baseline information to determine the current operational status and as justification for repairs or modification. Our credible services and validation has helped us in garnering multiple clients over the years. We stringently undertake HEPA tests for airflow velocity, uniformity, static pressure etc as per the standard norms. The HEPA filter integrity test is carried out as per IES recommendation, using an Imported Digital Photometer, which is, state-of-the-art and tamper proof. In fact, we offer our service for any make of Laminar Airflow/HEPA filtration equipment. The data gathered from these tests serve as baseline information to determine the current operational status and as justification for repairs or modification.

HEPA Filter Integrity Test ProcedureIES Recommendation (IES-RP-CC-002-86) :

• Di-Octyl-Phthalate (DOP) or equivalent Aerosol is introduced in the upstream HEPA filter, so as to produce uniform challenge concentration

• This concentration is set at 100% or full scale

• With this as reference, downstream HEPA filter face is scanned with Photometer Probe for Possible leaks

• All tests and checks are reported in a Scientific and easy-to-follow manner

• Our Test reports are comprehensive with all required details to satisfy any regulatory authority

• We can supply HEPA filters (both Minipleat and Separator Type) and Pre-filters of any size and any rating, for replacement requirements

• Minipleat filters are state-of-the-art machine made filters without aluminum separators to ensure superior performance and longer life.

The following tests will be carried-out as part of Validation of Clean Rooms/ Laminar Flow Units:

• HEPA filter integrity test using Photometer and Challenge Aerosol
• Particle count in each of the clean rooms as per US Federal Standards 209E.
• Checking and Setting Pressure gradient inside the rooms
• Air velocity and volume flow through HEPA filters
• Temperature & Humidity inside the Rooms
• Reporting all the above tests, with test procedure reference The test instruments used for the above test are calibrated to National Standards, such as NABL.

For Clean Rooms:

• We undertake validation on Call basis or periodically for a specified period
• Scope of work will be as mutually agreed and as mentioned in our offer.
• Our rates for One-time Service, AMC and Clean Room Validation jobs are most competitive, when compared with others offering the same service.
• We undertake general service, modification and up gradation of existing Clean Rooms.

Pressure balancing describes the mechanism to maintain the set temperature of the water (mix ratio) even if the pressure in either the hot or cold water line changes.

Cleanroom validation is provided by conducting a series of tests to qualify if a controlled environment is performing in accordance with process requirements and the applicable regulatory guidelines

HVAC system validation is required for pharmaceutical cleanroom validation, the sterile is validated through air flow pattern and velocity.

A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with pathogens requiring a defined biosafety level.

One of the most prevalent devices in a cleanroom environment is the Magnehelic gauge, however they still require more than a zero point calibration check.

Calibration of Laminar Flow Units and all HEPA filtration systems traceable to NABL. Already having more than 500 units/filters under contract all over India.

• HEPA filter Integrity (DOP/PAO Test
• Particle Count Test
• Air Velocity etc.